The inflatables were secured to the ground, but witnesses told authorities that the winds were strong enough to lift the bounce house about 20 to 30 feet into the air, and to send the slide toward the road, Reed said.
Police say the incident happened at Springwell Church in Taylors around Saturday afternoon.
"This afternoon, we held our annual Spring Carnival on our campus on Wade Hampton Blvd in Taylors SC".
The five children injured were taken by ambulance to a hospital nearby. Per WYFF, two of the children were severely injured, but the other three were able to walk.
"When the second bouncy house went up, I had thought my kids was on it", a witness said.
According to Fox Carolina, those attending the carnival reported that the house and slide were both staked to the ground but that the wind was ripped the straps loose, with many calling it a "freak accident".
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An unexpected wind gust, out of our control, lifted an inflatable amusement that was on our campus for the event. The bounce house reportedly struck a power line, but did not catch on fire.
Reed said the local power company had installed safeguards so that the grid system would automatically shut off the power lines in the event of an accident. They were able to respond before fire crews arrived, Reed said.
The severity of their injuries was not disclosed, but in a Facebook post to the church's page on Sunday, pastor David Pearson said two children remain hospitalized in "stable condition".
A power line was also knocked down during the incident. "There's no telling what would have happened", said Battalion Chief Ricky Reed.
"We join their families, in prayer, for their full recovery".