The plane hit the runway sideways and rolled 150 feet down a hill, Kanawha County Commission President Kent Carper told CNN affiliate WOWK-TV in Huntington.
"It departed the runway very quickly", Plante said.
The airport said in a news release it had contracted with Clean Harbors, a local environmental cleanup company, to help with any spills.
Plante says the 330 twin-engine turbo plane was operated by Air Cargo, a contractor for UPS. The National Transportation Safety Board is investigating the incident.
The FAA said on its website that Yeager Airport in Charleston isn't expected to reopen until Saturday morning.
It's not yet clear what caused the plane crash.
Plante said there was no indication of any issue with the aircraft before the crash. There didn't appear to have been a fire, he said.
Pier 1 Imports, Inc. (PIR): Investors Traded Stock
NBT Bank N A NY increased its position in shares of Yum! The firm has "Neutral" rating given on Monday, March 28 by Credit Suisse. Independent Advisor Alliance bought a new position in shares of Yum! Brands during the first quarter valued at about $292,000.
The plane crash delayed some flights at the airport, which was closed with air traffic diverted in the wake of the crash.
In the previous accident, a Bombardier Inc. The plane was carrying packages for UPS.
The pilot and co-pilot have both died, according to an airport official.
A county spokesperson says the plane crashed in to the hillside upon landing.
However, the commercial aviation industry has an "extremely poor" record of following this guidance.
Because of the fuel leak, West Virginia American Water has been notified an evaluating the situation.
One of the aircraft's wings was detached by the crash, according to WCHS.